Amorphous solid dispersion is a technology for solubility enhancement of drugs. Solubility of a large number of APIs is limited by their crystalline nature which results in poor solubility. If the absorption in the GI tract is acceptable, these compounds are classified as BCD class II. By dispersing the drug on a molecular level in a polymeric carrier, an amorphous state of the API is maintained in the drug product overcoming solubility issues. Shin-Etsu AQOAT® HPMCAS is the leading excipient in solubility enhancement by amorphous solid dispersion technology. Also PHARMACOAT® and HPMCP show good results in solubility enhancement.
Filtere Anwendungen nach:
Solvent free methods (HME)
Hot melt extrusion is an example of a solvent free process for the preparation of amorphous solid dispersion. The polymer is blended with the API and fed into an hot melt extruder. The carrier polymer is melting and the API dissolves in the polymer during the process. Kneading elements in the extruder add additional shear and energy to the system to create a homogenous extrudate. The extrudate is pelletized or milled and filled into capsules or compressed into tablets. Another option is to extrude filaments for 3D-printing and the tablet is printed.
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
Amorphous solid dispersions are also accessible by dissolving API and polymer carrier in a common organic solvent. Upon removal of the solvent, the dry product contains polymer with molecular dispersed, amorphous API. Processes examples utilizing organic solvents are spray drying, spray coating or co-precipitation.
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
3D printing tablets with Shin-Etsu AQOAT® (HPMCAS) [A-069]
Application of Shin-Etsu AQOAT® (HPMCAS) as a carrier in solid dispersion [A-028]
Application of Shin-Etsu AQOAT® (HPMCAS) in extended release (ER) matrix tablet formulation [A-070]
Aqueous based enteric formulation of Shin-Etsu AQOAT® (HPMCAS) containing amino acid as a stabilizer [A-049]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Coating parameters of a tablet batch size 5-100kg) [A-002]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Preparation of coating dispersion) [A-001]
Aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) (Using a small tabletop coating machine we coated tablet batch size of 300g) [A-006]
Aqueous enteric coating for lansoprazole using Shin-Etsu AQOAT® (HPMCAS) [A-059]
Aqueous enteric coating for soft gelatin capsule using Shin-Etsu AQOAT® (HPMCAS) [A-043]
Aqueous enteric coating for soft gelatin capsule with Shin-Etsu AQOAT® (HPMCAS) [A-062]
Aqueous enteric coating using Shin-Etsu AQOAT® (HPMCAS) for Mini-Tablets [A-053]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 1: solution and film properties [A-008]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 2: examples of coating applications [A-012]
Aqueous enteric coating with Shin-Etsu AQOAT® (HPMCAS): ammonia-neutralized method - part 3: stability of the coated preparations [A-013]
Aqueous fine particle coating with angled spray [A-044]
Aqueous formulation of Shin-Etsu AQOAT® (HPMCAS) containing an amino acid as stabilizer - comparison of formulation and process parameters on different coating equipment [A-055]
Comparative study of various coating methods with Shin-Etsu AQOAT® (HPMCAS) for pellets [A-060]
Comparison of mini-tablets enteric coating with Shin-Etsu AQOAT® (HPMCAS) using perforated pan or fluid bed coating equipment [A-056]
Concentration - viscosity curve of Shin-Etsu AQOAT® (HPMCAS) [A-064]
Direct compression of spray dried dispersion [A-072]
Dissolution behavior of coated fine particles by aqueous and solvent coating [A-045, H-013]
Effect of hot melt extrusion on the physicochemical properties of Shin-Etsu AQOAT® (HPMCAS) [A-017]
Effect of substitution of Shin-Etsu AQOAT® (HPMCAS) on dissolution profile of nifedipine solid dispersions (SD) prepared by Hot Melt Extrusion [A-032]
Enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS) [A-029]
Enteric coating of omeprazol granules using Shin-Etsu AQOAT® (HPMCAS) [A-031]
Enteric coating with Shin-Etsu AQOAT® (HPMCAS) by using water-ethanol solution [A-004]
Examples of aqueous dispersion coating using Shin-Etsu AQOAT® (HPMCAS) [A-003]
Impact of process parameters to solid dispersion particles [A-071]
Influence of alcohol on gastric resistance of Shin-Etsu AQOAT® (HPMCAS) [A-014]
IR spectrums of HPMCP and Shin-Etsu AQOAT® [H-017, A-054]
Mechanical properties of hot melt extruded amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-073]
Milling and downstream processing of hot melt extruded (HME) amorphous solid dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-067]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) (2) [A-047]
Minimum film formation temperature of Shin-Etsu AQOAT® (HPMCAS) [A-005]
Molecular weight of Shin-Etsu AQOAT® (HPMCAS) [A-007]
Nifedipine solid dispersion using Shin-Etsu AQOAT® - preparation by HME and downstream processing [A-051]
Partially neutralized coating technique using Shin-Etsu AQOAT® (HPMCAS) [A-037]
Scale-up of tablet enteric coating using the partially ammonia neutralized Shin-Etsu AQOAT® (HPMCAS) dispersion [A-068]
Solid dispersions (SD) using Shin-Etsu AQOAT® (HPMCAS) by holt melt extrusion [A-018]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in alkali solutions for cleaning media after coating operations [A-021]
Solubility of Shin-Etsu AQOAT® (HPMCAS) in mixed organic solvents [A-035]
Solution preparation of HPMCP and Shin-Etsu AQOAT® (HPMCAS) [H-019, A-058]
Stability of Shin-Etsu AQOAT® (HPMCAS) at high temperatures [A-010]
Taste masking coating for quinine tablets [A-061]
Taste masking coating using Shin-Etsu AQOAT® (HPMCAS) and PHARMACOAT® with controlled release [A-063, P-018]
Triacetin as an alternative plasticizer for aqueous dispersion with Shin-Etsu AQOAT® (HPMCAS) [A-057]
